Diagenics产品介绍

　更新时间：2019-07-28　点击量：1882

Diagenics成立于1994年，凭借其在过敏诊断和治疗领域多年的经验以及用于研究和常规实验室的ELISA试剂盒的供应和技术支持而建立了自己的名字。

Diagenics产品介绍

ELISA试剂盒和抗体

Diagenics的团队都具有研究或体外诊断行业的背景。自成立以来，我们代表瑞典公司Mercodia在英国。我们的产品组合现已扩展到包括来自众多精选ELISA试剂盒，抗体和相关产品的精选供应商的产品，以便我们可以为生命科学研究的几乎所有领域的客户提供支持。

Mercodia成立于1991年，开发，生产和销售基于ELISA技术的诊断试剂盒，用于临床和研究应用。

Mercodia ELISA试剂盒

如需订购Mercodia产品，请联系。

Mercodia成立于1991年，开发，生产和销售基于ELISA技术的诊断试剂盒，用于临床和研究应用。

临床和研究领域
糖尿病胰岛素是负责控制葡萄糖代谢的主要激素。胰岛素的分泌主要受血浆葡萄糖浓度的控制，并且激素具有许多重要的代谢作用。在胰岛素依赖性糖尿病（1型糖尿病）和一些其他病症如低垂体症中胰岛素浓度严重降低。胰岛素浓度在非胰岛素依赖型糖尿病（2型糖尿病），胰岛素瘤和某些类型的内分泌功能障碍（如库欣综合征和肢端肥大症）中升高。	心血管疾病氧化低密度脂蛋白（LDL）是一种致动脉粥样硬化斑块特异性蛋白，直接参与动脉粥样硬化病变的发生和发展。血管造影证实的冠状动脉疾病患者的血浆氧化LDL水平显着升高，现在越来越清楚氧化LDL的循环水平是冠状动脉粥样硬化的标志物。载脂蛋白（a）也被研究作为动脉粥样硬化的独立危险因素。 ELISA分析可用于两种分析物。

分析原则

ELISA序列测定和ELISA同时测定原理。

哺乳动物糖尿病

通过使用大鼠或小鼠胰岛素ELISA与人胰岛素ELISA（0.7％大鼠/小鼠交叉反应）的组合，可以在相同样品中与人胰岛素分开测定大鼠或小鼠胰岛素浓度。大鼠胰岛素ELISA，猪胰岛素ELISA，牛胰岛素ELISA，牛胰岛素ELISA，小鼠胰岛素ELISA，犬胰岛素ELISA，马胰岛素ELISA和大鼠Glicentin

人类糖尿病

确定血清或细胞培养基中的胰岛素，胰岛素原和C-肽是寻找I型和2型糖尿病有效治疗方法的有价值的工具。胰岛素ELISAs，C肽ELISAs，Leptin ELISA，载脂蛋白ELISA，胰高血糖素ELISA，Glicentin ELISA，GLP-1 NL-ELISA和Lispro NL-ELISA

心血管

Mercodia提供心血管疾病检测，重点关注动脉粥样硬化过程的不同机制。

使用说明

PDF包含各种Mercodia产品使用说明的文件。

Mercodia部分产品列表

Description	Rat Insulin ELISA	Ultrasensitive Rat Insulin ELISA	High Range Rat Insulin ELISA
Code No.	10-1250-01 10-1250-10	10-1251-01	10-1145-01
No. of tests	96/10x96	96	96
Measured antigen	Rat/mouse insulin	Rat/mouse insulin	Rat/mouse insulin
Standards ug/l	0, 0.15, 0.4, 1, 3, 5.5	0, 0.02, 0.05, 0.15 0.4, 1.0	0, 3.0, 7.5, 30.0, 75.0, 150.0
Calibration
Incubations (mins)	120+15	120+15	120+15
Sample/sample volume	serum/plasma 10ul	serum/plasma 25ul	serum/plasma 10ul
Sensitivity	≤0.15ug/l	1) ≤0.02ug/l	1.5 ug/l/ 263 pmol/l
Precision intra/inter cv%	<5.2%, <10.1%	1) <3% 1) <5%	<5%/<5%
Hook	>450 ug/l	450 ug/l	576 ug/l 100.8nmol/l
Cross-reactions	Human insulin 167% Insulin Lispro (Humalog®) 167% Human proinsulin 75% Human C-peptide <0.05% IGF-I <0.02% IGF-II <0.02% Rat C-peptide <0.001% Rat proinsulin 7% Mouse insulin 75% Porcine insulin 476% Sheep insulin 179% Bovine insulin 78% No interference by lipaemic, icteric or haemolysed samples	insulin (mouse) 81% insulin (human) 120% insulin (Humalog®)120% proinsulin (human) 71% C-peptide (human) <0.05% No interference by lipaemic, icteric or haemolysed samples	insulin (mouse) 81% insulin (human) 120% insulin (Humalog®) 120 proinsulin (human) 71% C-peptide (human)<0.05% No interference by lipaemic, icteric or haemolysed samples

Description	Porcine Insulin ELISA	Ovine Insulin ELISA	Bovine Insulin ELISA
Code No.	10-1200-01	10-1202-01	10-1201-01
No. of tests	96	96	96
Measured antigen	Porcine insulin	Ovine insulin	Bovine insulin
Standards ug/l	0, 0.02, 0.05, 0.15, 0.5, 1.5	0, 0.05, 0.15, 0.5, 1.5, 3.0	0, 0.05, 0.15, 0.5, 1.5, 3.0
Calibration	in-house reference	in-house reference	in-house reference
Incubations (mins)	120+15	120+15	120+15
Sample/sample volume	Serum/plasma 25ul	Serum/plasma 25ul	Serum/plasma 25ul
Sensitivity	≤0.01ug/l	≤0.025ug/l	≤0.025ug/l
Precision intra/inter cv%	<3.8% <3.9%	<3.7% <6.5%	<5.3% <7.0%
Hook	>1000ug/l	>1000ug/l	>1000ug/l
Cross-reactions	No interference by lipaemic, icteric or haemolysed samples	No interference by lipaemic, icteric or haemolysed samples	No interference by lipaemic, icteric or haemolysed samples

Description	Mouse Insulin ELISA	Ultrasensitive Mouse Insulin ELISA	Glucagon 10ul ELISA
Code No.	10-1247-01 10-1247-10	10-1249-01	10-1281-01
No. of tests	96/10x96	96	96
Measured antigen	Mouse Insulin	Mouse Insulin	Glucagon. validated for rat, mice, porcine & non-human primate.
Standards ug/l	0, 0.188, 0.5, 1.25, 3.75, 6.9	0, 0.025, 0.063, 0.188, 0.5, 1.25
Incubation (mins)	120 + 15	120 + 15	overnight+15
Sample/sample volume	serum/plasma 10ul	serum/plasma 25ul	Serum/plasma/cell culture
Sensitivity	≤0.2 ug/l	≤0.025 ug/l	1.5 pmol/l
Precision intra/inter cv%	<3.2%/<6%	<3%/<5%	Total 8.3 17.9%
Hook	>450 ug/l	>450 ug/l	>8 umol/l
Cross-reactions	No interference by lipaemic, icteric or haemolysed samples	No interference by lipaemic, icteric or haemolysed samples	Oxyntomodulin, human, rat, mouse 2.0% Oxyntomodulin, bovine, canine, porcine n.d. Mini-Glucagon n.d. GLP-1 n.d. GLP-2 n.d. Glicentin, human 1.0% Glicentin, mouse 7.0% Glicentin, rat 4.0%

Description	Rat C-peptide ELISA	Rat/Mouse proinsulin ELISA
Code No.	10-1172-01	10-1232-01
No. of tests	96	96
Measured antigen	Rat C-peptide	Rat and Mouse proinsulin
Standards pmol/l	c. 0 - 4000 (0 + 5 standards)	c. 0 - 2000 (0 + 5 standards)
Incubation (mins)	60 + 60 + 15	120+30
Sample/sample volume	serum/plasma 10ul	serum/plasma 25ul
Sensitivity	%td 3 pmol/l
Precision intra/inter cv%	<4.3%/<7.3%	<3.7%/<6.4%
Hook	400000pmol/l	90000pmol/l
Cross-reactions	Human C-peptide <0.001% Rat proinsulin 4.55% Rat insulin <0.01% No interference by lipaemic, icteric or haemolysed samples	Human insulin <0.0000001% Human proinsulin 2 - 10% (mean 5%) Human C-peptide <0.000001% Rat C-peptide <0.0000001% Rat insulin <0.000004% Mouse insulin <0.0003% Mouse C-peptide <0.00007% No interference by lipaemic, icteric or haemolysed samples

Description	High Range Porcine Insulin ELISA	Feline Insulin ELISA
Code No.	10-1223-01	10-1233-01
No. of tests	96	96
Measured antigen	Porcine Insulin	Feline Insulin
Standards	c. 0 - 75 g/l (0 + 5 standards)	0, 5, 35, 100, 350, 700 ng/l
Incubation (mins)	60 + 15	120+30
Sample/sample volume	serum/plasma 10ul	serum/plasma 10ul
Sensitivity	0.313ug/l	5ng/l
Precision intra/inter cv%	<2.3%/<5%	<4.8%/<8.9%
Hook	11500 ug/l	27600 ug/l
Cross-reactions	Porcine C-peptide <0.001% Porcine Proinsulin <0.2% Human insulin 28% Human Proinsulin <0.1% Human C-peptide <0.01% Aspart (NovoRapid) 0.7% Detemir (Levemir) <0.0000002% Glargin (Lantus) 5.4% Lispro (Humalog) <0.0000006% No interference by lipaemic, icteric or haemolysed samples	Aspart (NovoRapid®) 5.9% Detemir (Levemir®) <0.008% Glargin (Lantus®) 8.4% Lispro (Humalog®) <0.00000002% Glulisine (Apidra®) <0.0000007% Letsulin® , Caninsulin® 57.4% No interference by lipaemic, icteric or haemolysed samples

Description	Canine Insulin ELISA	Equine Insulin ELISA
Code No.	10-1203-01	10-1205-01
No. of tests	96	96
Measured antigen	Canine Insulin	Equine Insulin
Standards ug/l	0, 0.02, 0.05, 0.15, 0.50, 1.50	0, 0.02, 0.05, 0.15, 0.50, 1.50
Calibration	in-house porcine insulin reference	in-house porcine insulin reference
Incubation (mins)	120 + 15	120 + 15
Sample/sample volume	serum/plasma 25ul	serum/plasma 25ul
Sensitivity	≤0.01 ug/l	≤0.01 ug/l
Precision intra/inter cv%	<4.5%/<6.2%	<3.4%/<4.3%
Hook	>1000ug/l	>1000ug/l
Cross-reactions	porcine insulin 100% porcine C-peptide <0.001% porcine proinsulin <0.20% human insulin 28% human C-peptide <0.01% human proinsulin <0.1% NovoRapid 0.7% Levemir <0.0000002% Lantus 5.4% Humalog <0.0000006% No interference by lipaemic, icteric or haemolysed samples	porcine insulin 100% porcine C-peptide <0.001% porcine proinsulin <0.20% human insulin 28% human C-peptide <0.01% human proinsulin <0.1% NovoRapid 0.7% Levemir <0.0000002% Lantus 5.4% Humalog <0.0000006% No interference by lipaemic, icteric or haemolysed samples

Description	Porcine C-peptide ELISA	Rat Glicentin ELISA
Code No.	10-1156-01	10-1275-01
No. of tests	96	96
Measured antigen	Porcine C-peptide	Rat Glicentin
Standards pmol/L	c. 0—1500 (0 + 5 standards)	5—500 pmol/l
Incubation (mins)	120 + 60 + 15	overnight + 15
Sample/sample volume	serum/plasma/cell culture 10ul	Serum/plasma 10ul
Sensitivity	10 pmol/L	5 pmol/L
Precision intra/inter cv%	<3.7%/<3.8%	Total 7—14%
Hook	>30000 pmol/L	>11,000 pmol/l
Cross-reactions	Porcine insulin <0.05% Porcine proinsulin <0.02% Human C-peptide <0.003% Human proinsulin <0.01% Macaque C-peptide <0.006% Mouse C-peptide <0.007% Mouse insulin <0.13% Mouse proinsulin <0.002% Rat C-peptide 0.08% Rat insulin <0.002% Rat proinsulin <0.002%	Oxyntomodulin ND Mini-Glucagon ND GLP-1 ND GLP-2 ND Glucagon ND Human Glicentin <1.7% Mouse Glicentin 5.2%

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